NIX

[Nip3-like protein X] This mitochondrial protein is a member of the BCL2 family of proteins. It promotes cell death by apoptosis (Chen et al, 1999).

The protein is related to BNIP3. NIX is identical with BNIP3L and BNIP3-alpha (BNIP3A). The cDNA has been identified independently as BNIP3h.

NIX has been shown to interact with TSAP6. See: Adenovirus E1B 19 kDa protein.

Diwan et al (2007) have implicated NIX in erythroblast development. NIX is transcriptionally up-regulated during in vitro erythrocyte differentiation stimulated by ... ... ... ...
 
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Entry last modified: September 2006