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CD59

[CD59(+), CD59(-)]

This glycosylphosphatidylinositol-anchored glycoprotein (18-20 kDa) is expressed on all human peripheral blood leukocytes, erythrocytes, and several human cell lines. The protein is expressed also on endothelial cells, on the Schwann cell sheath of peripheral nerve fibers, neurons, microglia, oligodendrocytes, astrocytes, ependymal cells and certain epithelial cells such as acinar cells of the salivary gland, bronchial epithelium, renal tubules and squamous epithelium (Nose et al, 1990; Vedeler et al, 1994; Hideshima et al, 1990).

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