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pEL98

A murine cDNA clone identified in a search for mRNAs, which are abundant in established cell lines (Balb/c 3T3 cells), but less so in the corresponding parental counterparts (mouse embryo fibroblasts). Expression is increased in murine cells transformed with both activated oncogene and chemical carcinogen (Goto et al, 1988). pEL98 has been shown to be expressed in human monocytes, macrophages and polymorphonuclear leukocytes and appears to be involved in cell motility rather than influencing adhesiveness or phagocytic activity of these cells (Takenaga et al, 1994).

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