osteoblast/osteocyte factor of 45 kDa |
Osteoblast-specific cysteine-rich protein |
PPIA(84-100) |
||
Osteoblasts are cell that produce and maintain bone tissues and are being referred to also as osteogenic cells. For cells with phenotypical features of osteoblasts that play a role in tumor biolology see also: osteoblast-like cells, educated osteoblasts, osteomimicry.
Osteoblasts are derived from a common multipotent bone marrow progenitor that gives rise to both osteoblasts and hematopoietic cells (Dominici et al, 2004). Osteoblasts differentiate from mesenchymal stem cells, also known as bone marrow stromal fibroblasts. Upon termination of bone matrix synthesis, osteoblasts either undergo cell death by apoptosis
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