nur-77

[nuclear receptor-77] nur-77 is a member of a protein family encoding nuclear receptors. One of these, designated Nurr-1, appears to be expressed specifically in the brain (Law et al, 1992). The approved gene symbol is NR4A1 [nuclear receptor subfamily 4 group A member 1; nuclear receptor 4A1]. nur-77 is identical with NAK1 and NGFI-B (see: NGFI). The protein has extensive sequence homology to members of the steroid/thyroid hormone receptor superfamily (Davis et al, 1991).

nur-77 is an early response gene the transcription of which is rapidly and transiently stimulated by cross-linking of membrane immunoglobulin on ... ... ... ...
 
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Entry last modified: September 2017