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Th5 helper cells |
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[XTC mesoderm inducing factor] This heterodimeric factor, isolated from Xenopus laevis cells, is a member of the transforming growth factor-beta family (see: TGF-beta). Antibodies directed against TGF-beta-2 block the muscle inducing activity of XTC- cell conditioned medium.
The first inductive interaction in amphibian development is mesoderm induction, when a signal from the vegetal hemisphere of the blastula induces mesoderm from overlying equatorial cells. Mesoderm inducing factors cause isolated Xenopus laevis animal caps to form mesodermal cell types
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