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ODC factor

[ornithine decarboxylase inducing factor] This biochemically uncharacterized factor of approximately 79 kDa factor is isolated from the ascites fluid of Ehrlich ascites cells. It influences the differentiation of liver cells, reduces catalase activity and influences the metabolism of thyroid hormones (Imamura et al, 1991; Sasaki et al, 1983).

Another activity has been obtained from the conditioned medium of murine P388D1 cells (derived from macrophages). It also induces ornithine decarboxylase in the liver and spleen upon injection into mice. It is identical with IL1 or a molecule closely related to it (Endo et al, 1985).

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