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Neuromedin S

abbr. and approved gene symbol: NMS. This neuropeptide (ILQRGSGTAAVDFTKKDHTATWGRPFFLFRPRNamide), so named because of its specific expression in the suprachiasmatic nuclei (SCN) of the hypothalamus, has been identified by Mori et al (2005) in rat brain as a ligand for the G-protein-coupled receptor FM-4 / TGR-1, a receptor that also binds neuromedin U (see also: Miyazato M et al, 2008). Neuromedin S shares a C-terminal core structure with Neuromedin U.

The neuromedin S mRNA is highly expressed in the central nervous system, spleen and testis. In rat ... ... ... ... ... Subscribe to continue reading! ... ...

 

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