NLRC4 inflammasome |
NLRC5 inflammasome |
TSR1 |
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[NLR family, CARD domain containing 5] This is the approved gene symbol for proteins that have been described as NOD27 [caspase recruitment domain-containing protein-27], and CLR16.1 (see also: CLR family, NLR family; or nomenclature see also: Ting et al, 2008).
The gene encoding NLRC5 has been cloned by Cui et al (2010) from a human peripheral blood mononuclear cell cDNA library. Human and mouse proteins are 64 % identical. Kuenzel et al (2010) have reported the genomic organization of the human NLRC5 gene. Expression of NLRC5 in macrophages
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