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LTBP2

[Latent TGF-beta binding protein-2] LTBP2 is one of four extracellular matrix glycoproteins complexing TGF-beta isoforms in a latent form that allows targeting and activation of this growth factor (see also: LTBP1, LTBP3, LTBP4) (Oklu and Hesketh, 2000). In databanks the protein is found also as the product of the open reading frame C14orf141 [chromosome 14 open reading frame 141].

LTBP2 cDNA was isolated from a cDNA library prepared from human foreskin fibroblasts. The protein of 240 kDa is composed of 20 copies of an ... ... ... ... ... Subscribe to continue reading! ... ...

 

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