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KC

[keratinocyte chemoattractant; keratinocyte-derived chemokine; Keratinocyte Cytokine] A protein identified initially by its overexpression in murine keratinocytes, monocytes and macrophages following in response to PDGF and M-CSF (see also: early response gene). Its synthesis is induced also by TNF-alpha.

KC is involved in chemotaxis and cell activation of neutrophils. The murine product also binds to human neutrophils. The synthesis of KC in vascular endothelial cells is induced by ... ... ... ... ... Subscribe to continue reading! ... ...

 

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