GLP-1 receptor |
GLP2R |
senescent-cell death |
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[glucagon-like peptide-2] GLP-2 (bioactive form designated also GLP-2 (1-33)) is a peptide hormone of 33 amino acids (HADGSFSDEMNTILDNLAARDFINWLIQTKITD) encoded by the preproglucagon gene (see also: glucagon), which gives rise also to the related peptide hormones GLP-1 and Glucagon. GLP-2 corresponds to PG(126-158) [proglucagon(126-158)] (see: Holst, 1997).
The GLP-2 sequence is encoded carboxyterminal to the sequence of GLP-1 in the proglucagon gene (White and Saunders, 1986). Tissue-specific posttranslational processing of proglucagon
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