ERICE

[Evolutionarily Related Interleukin-1-beta Converting Enzyme] ERICE is a member of the ICE (caspase-1) subfamily of caspases, which includes caspase-1, caspase-4, and caspase-5. ERICE is known also as Caspase-13.

Overexpression of ERICE has been shown to induce cell death by apoptosis in HEK293 human embryonic kidney cells and MCF-7 breast carcinoma cells. ERICE can be activated by caspase-8, the apical caspase activated upon engagement of a death receptor belonging to the ... ... ... ...
 
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Entry last modified: June 2003