ELF-4 |
ELFADKVPKTAENFRAL |
Matrixins |
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This growth stimulating activity for fibroblasts has been identified in the conditioned medium of the ELF-153 human megakaryoblastic leukemia cell line established from a patient with acute myelofibrosis (Hassan et al, 1995).
The activity does not seem to be due to any of the known growth stimulating factors for fibroblasts, including PDGF, EGF, TGF-alpha or TGF-beta, TNF-alpha, IL1, IL2, IL4 or IL6, FGF, fibronectin, PF4 and factor VIII AG.
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