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CED2

[Cell death abnormality protein 2] a gene from Caenorhabditis elegans. The CED2 protein is involved in the engulfment of cells undergoing cell death by apoptosis (see also: efferocytosis). CED2 is considered to be the nematode counterpart of human Crk-2, an adaptor protein similar to v-crk sarcoma virus CT10 oncogene.

A complex of CED2, CED5, and CED10 defined in Caenorhabditis elegans is functionally analagous to the complex in mammalian cells consisting of Crk-2, DOCK180 and RAC1 ... ... ... ... ... Subscribe to continue reading! ... ...

 

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