pERp1

[plasma cell-induced ER protein 1; Plasma cell-induced resident endoplasmic reticulum protein 1; Plasma cell-induced resident ER protein 1] This resident ER protein has been identified by SHimizu et al (2009) as a component of the BiP chaperone complex. pERp1 expression is up-regulated substantially during B-cell to plasma cell differentiation and can be induced in B-cell lines by some activators of the unfolded protein response. In murine splenocytes stimulated with LPS, pERp1 interacts covalently via a disulfide bond with IgM monomers and noncovalently with other Ig assembly intermediates. ... ... ... ...
 
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Entry last modified: November 2013