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ephrins

short for: Eph family receptor interacting proteins (Eph Nomenclature Committee, 1997) The term Ephrins is a collective term for ligands of a large family of tyrosine kinase receptors known as Eph receptors [Erythropoietin-producing hepatoma receptors; Erythropoietin-producing hepatocellular carcinoma receptors] (Drescher, 1997; Tuzi and Gullick, 1994; Himanen and Nikolov, 2003). The name is derived from a hepatocellular carcinoma (hepatome) the cell line that produced erythropoietin, from which the first member of the family (see: EPH) was isolated (Hirai et al, 1987).

Ephrins can be divided into two structurally different groups (Flanagan et al, 1997). Class A ephrins ... ... ... ... ... Subscribe to continue reading! ... ...

 

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