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ZK1

This is known also as ZNF443 (approved gene symbol) or zfp443 [zinc finger protein 443]. ZK1 is a widely expressed DNA binding protein that regulates gene expression. Forced expression of ZK1 in 32D myeloid cells causes cell death by apoptosis following irradiation and growth factor withdrawal.

For other entries pertaining to cell death mechanisms see also the Apoptosis and Cell Death Dictionary section of this encyclopedia.

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Entry last modified: July 2012

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