XMK |
XMP |
GVVDILKGAAKDLAGHLATKVMNKL |
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[Xenopus laevis matrix metalloproteinase] The cDNA for this protease was cloned from Xenopus laevis embryos (Yang and Kurkinen, 1998). XMMP is a protein of 604 amino acids including a putative signal sequence of 22 residues. XMMP is structurally related to human MMP-19 and is distinguished from other matrix metalloproteinases by the occurrence of an inserted cysteine residue in the catalytic domain. These two proteins are considered to represent founding members of a subgroup of the MMP family. The XMMP gene is transiently expressed during Xenopus laevis embryo development (Yang et al, 1997). XMMP is considered the frog ortholog of
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