SOCS2

[Suppressor of cytokine signaling-2] This protein (Starr et al, 1997) is a member of the SOCS protein family. It functions as a regulator of cytokine signaling by interfering with signal transduction pathways involving mediators such as Janus kinases and STAT proteins and has been described independently as

CIS2 (also: CISH2) [Cytokine inducible SH2-containing protein-2],

STATI2 or SSI2 [STAT induced STAT inhibitor-2].

Metcalf et al (2000) have characterized the murine SOCS2 gene. Human ... ... ... ...
 
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Entry last modified: August 2008