S100Z

abbr. also S100-zeta [S100 calcium binding protein Z; S100 calcium binding protein-zeta] This protein belongs to the family of calcium-binding S100 binding proteins. The gene has been cloned by Gribenko et al (2001) from a human prostate cDNA library. S100Z (99 amino acids) shares 57 % and 52% sequence identity with S100A1 and S100P. The highest levels of S100Z are found in spleen and leukocytes. S100Z gene expression appears to be deregulated in some tumor tissues, compared to expression in their normal counterparts. Carlsson et al (2005) have reported upregulated expression of S100Z in breast cancer.

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Entry last modified: February 2012