nucleic acid editing |
nucleobindin-1 |
ADAMTS5 |
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abbr. NUC. The factor has been renamed nucleobindin-1, following the identification of a related calcium-binding protein, termed nucleobindin-2. The approved gene symbol is NUCB1.
This factor of 55 kDa is found in the conditioned medium of KML1-7 cells derived from lupus-prone MRL/lpr mice (Kanai et al, 1993). The amino acid sequences of Nucleobindin are highly conserved between mouse and humans. The polypeptide predicted from the cDNA sequence possesses a signal sequence, a leucine zipper
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