NAV2

(approved gene symbol) [neuron navigator 2]. NAV2 is one member of a family of related proteins (see: NAV1, NAV3) (Maes et al, 2002). The cDNA for this protein has been identified independently as KIAA1419. The same protein has been described as RAINB1 [retinoic acid inducible in neuroblastoma cells] with a possible role in neurite outgrowth, and as HELAD1 [helicase, APC down-regulated 1] with a role in cancer cell apoptosis.

Sequence homology suggests that the protein is the mammalian counterpart of Caenorhabditis elegans unc-53 (Merrill et al, 2000). It is therefore being referred to also as UNC53H2 [ ... ... ... ...
 
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Entry last modified: June 2014