Myddosome
[myddosomes]
The myddosome is an oligomeric signaling complex consisting of the adaptor protein MyD88 and IRAK4 kinase with stoichiometries of 7:4 and 8:4 (Watters et al, 2007; Motshwene et al, 2009).
MyD88 is a protein required for signaling of toll-like receptors with the exception of TLR3 (O'Neill and Bowie, 2007). MyD88 is required also for intracellular signaling in response to IL1 and IL18 (O'Neill, 2008). IRAK kinases (IRAK1, IRAK2, and IRAK4) are kinases activated by Toll-like receptors via MyD88. Subsequent autophosphorylation
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted !
COPE - with 54500+ entries the most comprehensive cell-to-cell communication knowledge base
Extensive In-depth and In Context Information covering terminology,
nomenclature, concepts, strategies & complexities of cellular communication, including
Acute phase proteins |
Angiogenesis |
Antimicrobial & host defense peptides |
Apoptosis & other forms of cell death |
CD antigens |
Cell lines |
Cell reprogramming |
Chemokines |
Cryptides |
Cytokines & Growth factors |
CytokineTopics |
Eukaryotic cell types & expression profiles |
Hematopoiesis |
Hormones |
Inflamation & inflammatory mediators |
Innate Immunity |
Metalloproteinases |
Microvesicles / Microparticles |
Moonlighting proteins & cryptides |
Neuropeptides |
Non-coding RNAs |
Pathogenicity & Virulence Factors |
Pattern recognition receptors |
Peptide sequences |
Protein domains |
Regulatory peptide factors |
Viroceptors |
Virokines and more.
Full COPEing for subscribers:
Access to Alphabet bar, Freetext search, Leafing/browsing functions, Internal Backlinking,
Topic-specific introductions, Topic-specific integrated subdictionaries, Scientific references with PubMed links
with a 15 USD/month subscription at
Cells-Talk.com
See example pages at the bottom of the Cells-Talk.com home page
THE SMART ONES COPE
The others just sisyphos around
|
ENTRY LAST MODIFIED: November 2011
| # |
A |
B |
C |
D |
E |
F |
G |
H |
I |
J |
K |
L |
M |
N |
O |
P |
Q |
R |
S |
T |
U |
V |
W |
X |
Y |
Z |
U L T R A P O S S E
N E M O O B L I G A T U R
cope.cgi Version 1.41 [08.12.2020]. (c) JI. Powered by Perl 5.032001. key=34976