LL-37

[leucine-leucine-37] see: Cathelicidins, which also contains further information for bioactive fragments of LL-37. For the Rhesus monkey counterpart see: RL-37. For a designer peptide based on LL-37 see also: IDR-1 [innate defense regulator peptide 1].

De Yang et al (2000) have reported that LL-37 employs FPRL1 as a receptor and acts as a chemoattractant for neutrophils, monocytes, and T-cells. LL-37 also has chemotactic activity toward mast cells (Niyonsaba et al, 2002), and stimulates mast cell degranulation (Niyonsaba et al, 2002).

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Entry last modified: February 2016