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Cathelicidins

a family of antibacterial peptides with cytotoxic activities at higher concentrations. The proteins are unrelated to defensins. They contain a conserved N-terminal cathelin proregion - the cathelin domain - and a variant C-terminal antibacterial domain (Zanetti et al, 1995; Zanetti, 2004; Lehrer and Ganz, 2002). Removal of the cathelin domain liberates the active antimicrobial peptide.

CATHL1 [cathelicidin 1] is Bac1 (Bactenecin 1, Bactenecin) and corresponds to Fowlicidin-1

CATHL2 [cathelicidin 2] is Bac5 ( ... ... ... ... ... Subscribe to continue reading! ... ...

 

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