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[LGR4(+), LGR4(-)]

[leucine-rich repeat-containing G-protein-coupled receptor 4] LGR4 was identified originally as an expressed sequence tag and named by Hsu et al (1998). The human gene has been cloned by Loh et al (2001). The protein contains multiple N-terminal leucine-rich repeats. The approved gene symbol is GPR48 [G-protein-coupled receptor-48].

LGR4 can act as a receptor for R-spondin-1, R-spondin-2, R-spondin-3, and R-spondin-4 (De Lau et al, 2011; Glinka et al, 2011; Carmon et al, 2011). Deng C et al (2013) have reported that Norrin, which is also capable of activating ... ... ... ... ... Subscribe to continue reading! ... ...


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