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KC-HSF

[Kupffer cell derived hepatocyte stimulating factor] This biochemically uncharacterized factor of approximately 100 kDa is found in the conditioned medium of rat Kupffer cells after cell activation with bacterial lipopolysaccharides (Kurokawa et al, 1988). It stimulates more than 100-fold the synthesis of one of the acute phase proteins, Alpha-2-Macroglobulin, in adult rat hepatocytes. The factor is not identical with IL1.

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