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IP17

[Interferon-induced 17 kDa protein] This factor of 17 kDa has been identified as an activity chemotactic for neutrophils in the lysate of red blood cells of mice infected with murine malaria, Plasmodium yoelii. IP17 is identical to a murine homolog of ISG15 (UCRP), a member of the ubiquitin family of proteins that are inducible by IFN-beta. IP17 shows specific chemotactic activity for neutrophils and activated neutrophils and induces the release of eosinophil chemotactic factors.

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