IDF-45

[inhibitory diffusible factor-45] This monomeric factor of 45 kDa is isolated from the conditioned medium of confluent murine 3T3 cells (Blat et al, 1989). The known aminoterminal sequences demonstrates that this factor is related to rat and murine IGFBP3 [insulin-like growth factor binding protein-3] and it has been suggested that IDF-45 be called murine IGFBP3 (Blat et al, 1992).

IDF-45 binds IGF (see also: IGFBP). It reversibly inhibits the growth of chicken fibroblasts and some other cell types (Blat et al, 1989). IDF-45 also inhibits the ... ... ... ...
 
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Entry last modified: January 2002