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HMGB3

[high mobility group box-3] This protein is known also as HMG4 [high mobility group protein-4] (Vaccari et al, 1998) and HMG2A [high mobility group protein-2A]. HMGB3 is a DNA-binding and bending protein (Brown and Anderson, 1986; Lee and Thomas, 2000). The protein contains a HMG box and belongs to the family of so-called high mobility group of nonhistone chromosomal proteins. The cDNA of the protein, which is encoded by an X-linked gene, has been cloned by Wilke et al (1997).


Role in innate immunity

Yanai et al (2009) have reported that HMGB3, together with HMGB1 and HMGB2 ... ... ... ... ... Subscribe to continue reading! ... ...

 

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