HMGB1 |
HMGB3 |
d/tPRP |
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(approved gene symbol) [high mobility group box 2] abbr. also: HMG2 [high mobility group protein 2] HMGB2 belongs to the family of so-called high mobility group of nonhistone chromosomal proteins. cDNA and genomic sequences have been described by Majumdar et al (1991) and Shirakawa and Yoshida (1992).
HMGB2 shares >80 % amino acid sequence identity with the ubiquitous HMGB1 and the embryo-specific HMGB3. All three proteins are characterized by the presence of two basic DNA binding HMG box domains (Box A and Box B) followed by a long acidic tail (Bustin, 1999). DNA binding is without sequence specificity. Like HMGB1
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