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Eta-1

[early T-lymphocyte activation protein 1] This gene was identified as a murine cDNA expressed abundantly after T-cells cell activation (Patarca et al, 1989). Eta-1 may constitute the most abundant molecule secreted by T-lymphocytes after cell activation. Eta-1 is expressed at very high levels in T-cells from autoimmune MRL mice, which develop murine lupus (see also: lpr), but not normal mouse strains and in a CD4(-) CD8(-) CD45R(+) T-cell clone (Patarca et al, 1990). The protein is secreted also by activated macrophages ... ... ... ...
 
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Entry last modified: March 2006



 
 
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