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CD antigens

[CD antigen]

[CD = cluster of differentiation, cluster of determinants] Lymphocytes, in the course of development from precursor cells into functionally mature forms (see also: hematopoiesis), display a complex pattern of surface antigens, some of which are acquired at certain stages while others are lost.

These surface antigens (identified by the acronym CD followed by a number) were identified initially by monoclonal antibodies and the designations of the antibodies were used often as synonyms for the cell surface proteins they detected, giving rise to a plethora of different names (see: CD antigens MiniCOPE Dictionary). These antigens are frequently being referred to as Leukocyte differentiation antigens.

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