lymphocyte promoter factors |
Lymphocyte-specific interferon response factor |
BCL2 inhibitor of transcription 1 |
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[lymphocyte, lymphocyte-derived]
Lymphocytes are the primary cells of an immune response. Most lymphocytes are located in lymphoid tissues and only a very small portion circulate in the blood. The most important types are the T-cells, B-cells, and mature B-cells (plasma cells).
The process leading to the formation of lymphocytes is called lymphopoiesis. Initial lymphopoiesis takes place in bone marrow. Maturation takes places in lymph nodes, and the thymus. These initial phases of lymphopoiesis do not require exposure of the cells to antigens. An antigen-dependent phase of lymphopoiesis involves a second cycle of differentiation and proliferation when the
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