cardiac ventriculocytes |
CARDIF |
SFME |
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[CARD containing IL1-beta converting enzyme-associated kinase] This protein contains a serine/threonine kinase domain and a carboxy-terminal caspase activation and recruitment domain (CARD). The protein has been renamed RIPK2 [receptor-interacting serine/threonine kinase 2] and is identical with RIP2, and RICK. A databank synonym for this protein is CARD3, caspase recruitment domain-containing protein-3].
Overexpression of CARDIAK induces the activation of transcription factor NF-kappa-B and c-Jun N-terminal kinase (JNK). CARDIAK has been shown to interact with the
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