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Bio-Immunomodulator

abbr. Bim. This biochemically uncharacterized heat-stable protein of 12.7 kDa has been isolated from the conditioned medium of cultured mouse bone marrow cells.

The protein shows anti-implantation and anti-tumor activities. Administration of the factor improves immunocompetence in vivo, stimulating the activity of macrophages, T-cells, B-cells, and the phagocytic activity of neutrophils (Ghoshal et al, 1998, 1994). The factor also modulates the activity of Na-K ATPase and Ca-Mg ATPase.

The protein has been shown to act as an inhibitor of angiogenesis in the pregnant rat model, inducing the disintegration of uterine myometrium and ... ... ... ... ... Subscribe to continue reading! ... ...

 

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