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BM88

The cDNA encoding this protein (identified by a monoclonal antibody of the same name) has been cloned by Gaitanou et al (2001). Human BM88 shares 79.9 % and 76.4 % amino acid identity with mouse and porcine BM88, respectively. The approved gene symbol is CEND1 [cell cycle exit and neuronal differentiation 1].

The protein is expressed in neurons and Purkinje cells (Gaitanou et al, 2001; Politis et al, 2007; Liang JD et al, 2001; Patsavoudi et al, 1989, 1995). BM88 has been shown to be an early marker of proliferating precursor cells that will differentiate into the neuronal lineage (Koutmani et al, 2004).

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