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BCLg

[BCLgonad] The cDNA for this protein has been isolated by Guo et al (2001), following a search in EST databanks for sequences with homology to the anti-apoptotic protein BCL2. The approved gene symbol is BCL2L14 [BCL2-like-14].

There is a short (BCLgS; 252 amino acids) and a long (BCLgL; 327 amino acids) variant. Both proteins contain a candidate BH3 domain. The long variant contans a BH2 domain. Strong expression of the long variant is seen in lung, pancreas, prostate, and testis. The short form appears to be expressed only in testis.

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