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B7-H6

[B7 homolog-6] The approved gene symbol is NCR3LG1 [NCR3 ligand 1; natural cytotoxicity triggering receptor 3 ligand 1]. The gene has been identified and named B7-H6 by Brandt et al (2009). This encoded protein belongs to the B7 family (Flajnik MF et al, 2012; Jung and Choi, 2013) and shares greatest similarity with B7-H1 and B7-H3. The full-length B7-H6 gene appears to be absent in mice. The protein contains an inhibitory sequence motif (ITIM), an SH2 binding domain, and an SH3 binding motif.


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