ATG16L1

[autophagy related 16 like 1; Autophagy-related protein 16-1] also: ATG16L, ATG16A, APG16L [APG16 autophagy 16-like]. A databank synonym is WDR30 [WD repeat domain 30; WD repeat-containing protein 30] as the protein contains WD40 domains (Mizushima N et al, 2003).

This protein plays an essential role in autophagy by forming an ∼800 kDa protein complex with ATG12 and ATG5. The ATG16L complex functions as an E3-like enzyme that provides a scaffold for producing lipidated LC3-II ... ... ... ...
 
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Entry last modified: September 2017