ACKR3

[atypical chemokine receptor 3] This is an alternative designation and the approved gene symbol for the chemokine receptor RDC1, which is known also as CXCR7. This receptor is an example of an atypical chemokine receptor that acts as a decoy receptor, which is characterized by an inability to mount classical receptor signalling following ligand binding. For nomenclature see also Bachelerie F et al (2013). The receptor is known to bind CXCL11 and CXCL12 (Bachelerie et al, 2014, and references cited therein).

A functional ortholog of human ACKR3 in zebrafish that binds the chemokine CXCL12 ... ... ... ...
 
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