744.1
Name of a DNA clone encoding a gene expressed after cell activation of T-cells with various mitogens (Zipfel et al, 1989; Obaru et al, 1986). Irving et al (1990) have determined the genomic structure. The cDNA encodes human MIP-1-beta. See: MIP (macrophage inflammatory protein).
The factor is known also as SCYA4. The approved gene symbol is CCL4. The gene is present as an additional copy, referred to as 744.2.
This factor is known mainly because of its chemotactic activity. For an unrelated function as an antimicrobial peptide in innate immunity see:
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