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464.1

Name of a DNA clone encoding a gene expressed after cell activation of T-cells with various mitogens. The cDNA encodes human MIP-1-alpha. See: MIP (macrophage inflammatory protein).

The factor is known also as SCYA3 and the approved gene symbol is CCL3. The gene is present as an additional copy, referred to as 464.2 (SCYA3L1).

This factor is known mainly because of its chemotactic activity. For an unrelated function as an antimicrobial peptide in innate immunity see: CCL3 ... ... ... ... ... Subscribe to continue reading! ... ...

 

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