Piecemeal degranulation |
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The term troxis necrosis ("nibbling necrosis" has been suggested for this term (Wang et al, 2001).
Piecemeal necrosis is observed in hepatitis of viral or autoimmune origin. The term describes the piecemal removal of hepatocyte cytoplasm, which is mediated by lymphocytes binding to hepatocytes and repetitive steps of endocytosis, which removes parts of the hepatocyte cytoplasm and the nucleus (Wang et al, 2001; Kerr et al, 1979). Kerr et al (1979) have suggested that piecemeal necrosis is a specific form of cell death by apoptosis.
For other entries pertaining to cell death mechanisms see also the Apoptosis and Cell Death Dictionary section of this encyclopedia.
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