phagophore |
phalangeal cells |
Osteocrin(81-102) |
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This term (also: primary phagocytosis; sometimes whole cell phagocytosis) refers to a form of cell death involving the destruction of viable cells by phagocytes through the process of phagocytosis (for overview see: Brown and Neher, 2012, 2014; Brown et al, 2015) (see also: cell-in-cell death). For a process involving cell death of the phagocyte rather than the ingested cell see also: Phagocytosis-induced cell death.
In principle, phagoptosis is governed by two different kinds of signals, i.e., the untimely loss of don't-eat-me signals, for example CD47, from the cell surface or the aberrant exposure of eat-me signals, for example
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