p53CSV

[p53-inducible cell-survival factor] The approved gene symbol is TRIAP1 [TP53 regulated inhibitor of apoptosis 1]. A databank synonym is WF-1.

p53CSV, also designated HSPC132 by the authors, has been identified by Park and Nakamura (2005). The reduction of expression enhances cell death by apoptosis, whereas overexpression protects cells from apoptosis caused by DNA damage. p53CSV expression is induced significantly under low levels of genotoxic stress, but not when DNA damage is severe. p53CSV can modulate apoptotic pathways through interaction with ... ... ... ...
 
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Entry last modified: March 2012