leucosulfakinin II |
Leucrocin I |
DEVMLQD |
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Two peptides with a sulfated tyrosine residue, termed Lem-SK-1 (leucosulfakinin) (EQFEDYGHMRFamide) and Lem-SK-2 (leucosulfakinin II) (pQSDDYGHMRFamide) have been isolated from the Madeira cockroach, Leucophaea maderae (Nachman et al, 1986, 1986). These peptides belong to a class of neuropeptides structurally and functionally similar to the vertebrate brain-gut peptides cholecystokinin / gastrin (see: sulfakinins).
Leucosulfakinin shows myotropic activity in the hindgut. The intestinal myotropic activity of leucosulfakinin II is analogous to that of the
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