lactalbumin-alpha(109-114) |
lactase-like |
Mas receptor |
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Lactaptin has been identified as a proteolytic fragment of human kappa-casein and corresponds to casein-kappa(57-134) (kappa-casein(57-134)) of casein-kappa (Nekipelaya et al, 2008). Lactaptin acts as an anticancer peptide. Semenov et al (2010) have shown that induces cell death by apoptosis in cultured human MCF-7 adenocarcinoma cells in a process involving caspase-7 activation. It also reduces the viability of A549 and Hep-2 cells without causing apoptosis. Non-malignant human mesenchymal stem cells are completely resistant to lactaptin action.
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