innate lymphoid cells

abbr. ILCs. This general term refers to various populations of immune cells (for nomenclature see also: Spits et al, 2013; for an overview see also: Gladiator and LeibundGut-Landmann, 2013; Kumar, 2014; Cortez and Colonna, 2016; Moretta and Locatelli, 2016; Mjösberg and Spits, 2016; Gronke et al, 2016); for an overview of different subtypes see: Dzopalić T et al, 2019).

These cells are of lymphoid origin, but in contrast to lymphocytes don't express RAG-dependent rearranged specific antigen-specific receptors. They can produce an array of effector cytokines that in variety match that of T-helper cell subsets and can be distinguished from one another by the expression of various other markers. For a common ... ... ... ...
 
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Entry last modified: October 2019